Deepondé

Glutathione Barrier Cream

A Glutathione (5,000 ppm) barrier-finishing cream with a 5-type ceramide complex, Squalane, and 6 peptides that seals in tone correction while strengthening the skin's protective layer.

$26.00

Size

(5)

  • Seals in the tone correction work of the Glutathione Toning Ampoule.
  • 5-type ceramide complex (NP, NG, NS, AP, AS, EOP) for comprehensive barrier rebuilding.
  • Squalane for fast-absorbing, non-greasy protective moisture all year round.
  • 6 peptides + Niacinamide for firmness and radiance support at the final step.

Vegan formula
Fragrance-free
99% purity Glutathione (30,000 ppm)
Free from 8 types of preservatives (including parabens)
Dermatologically tested

Estimated delivery between June 09 and June 11. Order within .

Deepondé | Glutathione Barrier Cream | Cream - Front view on white background

Glutathione Barrier Cream

$26.00

$26.00

Protects the progress you've made

Applied as the final step after the Glutathione Toning Ampoule, this cream seals in tone-correction results and prevents environmental factors from disrupting the skin.

Five ceramide types for a real barrier

Five distinct ceramide types (Ceramide NP, NG, NS, AP, AS) plus Phytosphingosine and Cholesterol work together to rebuild and reinforce the skin's lipid matrix.

Squalane for non-greasy moisture

Squalane is structurally similar to skin's own sebum, absorbing without the heavy or occlusive feeling of heavier creams. The protective layer it forms is breathable in all seasons.

All-in-one glow + firmness finishing step

Glutathione (5,000 ppm), Niacinamide, six peptides, and Adenosine continue addressing tone, clarity, and elasticity even after your routine is complete.

Clinical Trial Results

Clinically proven. Every result below comes from independent testing. Exact figures, no estimates. Individual results may vary.

Hydration That Lasts

Hydration That Lasts

After a single application, surface hydration jumped from 38.45 to 66.12 — and was still at 44.28 after 250 hours, vs. 38.46 for untreated skin. Deep hydration followed the same pattern, remaining elevated at 37.42 at the 250-hour mark.


What this means for you:

One application keeps skin measurably more hydrated for over 10 days. You're not just moisturizing for today.

Barrier Recovery After Damage

Barrier Recovery After Damage

After SLS-induced barrier damage, skin treated with the cream recovered elasticity to 0.81 and hydration to 38.87 after 2 weeks — both surpassing the pre-damage baseline, vs. 0.75 and 33.36 for untreated skin.

What this means for you:

This test intentionally broke the skin barrier, then measured recovery. The cream didn't just restore skin to where it started — it came back stronger. That's genuine barrier repair.

Results based on instrumental testing. SLS model is a standard method for simulating barrier disruption in cosmetic efficacy research. Individual results may vary.

5-Type Ceramide Complex + Squalane

Ceramides are the skin's natural barrier lipids—and this cream includes five distinct types (NP, NG, NS, AP, AS, EOP) alongside Phytosphingosine and Cholesterol to create the most complete barrier support in the Deepondé range. Squalane mirrors skin's own oils, allowing the cream to absorb quickly and protect effectively without heaviness or shine.

Water (Aqua), Glycerin, Butylene Glycol, Squalane, Bis-Hydroxyethoxypropyl Dimethicone, Niacinamide, Dicaprylyl Ether, Polyglyceryl-3 Methylglucose Distearate, Caprylic/Capric/Myristic/Stearic Triglyceride, Cetearyl Alcohol, Methyl Trimethicone, Benzyl Glycol, Palmitic Acid, Stearic Acid, Helianthus Annuus (Sunflower) Seed Oil, Glyceryl Stearate, Glutathione (5,000 ppm), Tromethamine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Glucoside, Behenyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Theobroma Cacao (Cocoa) Seed Butter, Allantoin, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Disodium EDTA, Adenosine, Hydrogenated Lecithin, Sorbitan Isostearate, Polyglyceryl-10 Stearate, Tocopherol, Panthenol, Sodium Ascorbyl Phosphate, Ceramide NP, Caprylyl Glycol, 1,2-Hexanediol, Phytosphingosine, Cholesterol, Ceramide NG, Ceramide NS, Ceramide AP, Ceramide AS, Pyridoxine, Folic Acid, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Tripeptide-1, Copper Tripeptide-1, Acetyl Hexapeptide-8, Biotin, Hexapeptide-9, Cyanocobalamin, Nonapeptide-1, Thiamine HCl, Beta-Carotene, Riboflavin, Linoleic Acid, Ceramide EOP

Deepondé Difference

Deepondé uses a proprietary 354-hour extraction process (Vintage 3310™)—steaming, drying, and vacuum-concentrating Tremella Fuciformis repeatedly to maximize polysaccharide potency. This level of commitment to a single ingredient is what makes Deepondé's plant-based hydration different from the rest.

For Best Results

How to Use

As the final step of your skincare routine, take an appropriate amount and gently apply to the face and neck, spreading smoothly until absorbed.


Extra tips:

  • Apply both morning and night for continuous protection.
  • In the morning, follow with SPF 30+ to protect tone-correction results from UV exposure.
  • Use directly after Glutathione Toning Ampoule for the full Deepondé Glutathione routine.
  • Works well as the sealing final layer alongside other serums or ampoules.

For external use only. Avoid contact with eyes. If eye contact occurs, rinse thoroughly with water. If irritation or rash persists, consult a doctor. Keep out of reach of children. To ensure skin compatibility, conduct a patch test before use.

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FAQs

View all FAQs

Glutathione Barrier Cream is particularly suited for those finishing a tone-correcting routine who want to protect and extend those results. It's also excellent for skin with a weakened or disrupted barrier—anyone experiencing sensitivity, dullness, or easy redness will benefit from the ceramide complex.

Yes—that's when it's most useful. A weakened barrier is one of the main reasons skin looks dull and uneven. This cream stabilizes and protects without adding any additional irritation.

No. Squalane is the primary oil base—it's skin-identical, meaning it absorbs quickly and leaves a comfortable finish without greasy heaviness. The overall texture is designed for day and night use in all seasons.

No. The high-adherence texture means it sits smoothly under morning makeup without disruption. It helps subsequent products adhere evenly and comfortably.

Yes. Glutathione Barrier Cream is designed to be the final step in any routine. When used as the finishing layer over Glutathione Toning Ampoule, you can expect a synergistic effect that combines barrier repair, moisture, tone support, and firmness into one cohesive regimen.

General Questions

Each Deepondé product has a recommended placement in the routine, which you'll find on its product page under How to Use. As a general principle: lighter textures and calming first steps go earlier; sealing and moisture-barrier products go last. If you're building a routine from the beginning, Signature Origin 100 is the place to start.

Every formula in the Deepondé range is developed with a minimal ingredient list, free from fragrance, essential oils, and the most common skin-irritating additives. Each product is dermatologically tested. That said, individual skin varies — a patch test before first use is always recommended.

All Deepondé products are formulated for daily and night use. Some, like the sheet mask, work well as a weekly ritual or on-demand step; others are designed to be part of your morning and evening routine. Specific guidance is on each product page.

Deepondé is built around a slow but sure approach. Most people notice an immediate change in comfort and texture from the first use. Visible shifts — in elasticity, tone clarity, or pore appearance — develop over several weeks of consistent use. Results compound quietly rather than announcing themselves early.